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UNC5B Protein (Fc Tag)

UNC5B Origin: Rat Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
Catalog No. ABIN7321225
  • Target See all UNC5B Proteins
    UNC5B (Netrin receptor UNC5B (UNC5B))
    Protein Type
    Recombinant
    Origin
    • 6
    • 1
    • 1
    • 1
    Rat
    Source
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This UNC5B protein is labelled with Fc Tag.
    Purpose
    Recombinant Rat UNC5B/UNC5H2 Protein (Fc Tag)
    Sequence
    Met1-Asp373
    Characteristics
    A DNA sequence encoding the rat UNC5B (NP_071543.1) (Met1-Asp373) was expressed with the Fc region of human IgG1 at the C-terminus.
    Purity
    > 85 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method
    Top Product
    Discover our top product UNC5B Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    UNC5B (Netrin receptor UNC5B (UNC5B))
    Alternative Name
    UNC5B/UNC5H2 (UNC5B Products)
    Synonyms
    unc5h2 Protein, 6330415E02Rik Protein, A630020F16 Protein, D10Bwg0792e Protein, Unc5h2 Protein, UNC5H2 Protein, p53RDL1 Protein, UNC5C Protein, UNC5B Protein, p53rdl1 Protein, unc-5 netrin receptor B Protein, unc-5 netrin receptor B L homeolog Protein, unc5b Protein, Unc5b Protein, UNC5B Protein, unc5b.L Protein
    Background

    Background: The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. In addition, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis.

    Synonym: UNC5B

    Molecular Weight
    65.7 kDa
    NCBI Accession
    NP_071543
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