NMNAT2 Protein (His tag)
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- Target See all NMNAT2 Proteins
- NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This NMNAT2 protein is labelled with His tag.
- Purpose
- Recombinant Human NMNAT2/NMNAT-2 Protein (His Tag)
- Sequence
- Met 1-Gly307
- Characteristics
- A DNA sequence encoding the human NMNAT2 (Q9BZQ4-1)(Met1-Gly307) was fused with a polyhistide tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product NMNAT2 Protein
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Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 1-307) protein (His tag)
NMNAT2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 1-302) protein (GST tag)NMNAT2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 1-307) protein (GST tag)NMNAT2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 208-307) protein (GST tag)NMNAT2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 1-307) protein (Strep Tag)Crystallography grade NMNAT2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 1-307) protein (Strep Tag)Crystallography grade NMNAT2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)NMNAT2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 5 mM DTT, 10 % glycerol, pH 8.0
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))
- Alternative Name
- NMNAT2/NMNAT-2 (NMNAT2 Products)
- Synonyms
- zgc:73048 Protein, wu:fj59g01 Protein, NMNAT2 Protein, C1orf15 Protein, PNAT2 Protein, AI843915 Protein, D030041I09Rik Protein, PNAT1 Protein, nicotinamide nucleotide adenylyltransferase 2 Protein, nmnat2 Protein, NMNAT2 Protein, Nmnat2 Protein
- Background
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Background: NMNAT2, also known as NMNAT-2, belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family. NMNAT is a central enzyme in NAD+ biosynthesis, transferring the adenylyl moiety of ATP to nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) resulting in the formation of NAD+ or NaAD+ and the release of pyrophosphate. NMNAT2 is predominantly expressed in human pancreas, insulinoma as well as in the brain, especially in the cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. Immunofluorescence microscopy localized endogenous NMNAT2 to the Golgi apparatus in human cell line. Endogenous NMNAT2 seem to be a labile axon survival factor, because specific depletion of NMNAT2 is sufficient to induce Wallerian-like degeneration of uninjured axons which endogenous NMNAT1 and NMNAT3 cannot prevent. Thus endogenous NMNAT2 represents an exciting new therapeutic target for axonal disorders.
Synonym: C1orf15,PNAT2
- Molecular Weight
- 35.8 kDa
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