RCN3 Protein (His tag)
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- Target See all RCN3 Proteins
- RCN3 (Reticulocalbin 3, EF-Hand Calcium Binding Domain (RCN3))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RCN3 protein is labelled with His tag.
- Purpose
- Recombinant Mouse Reticulocalbin 3/RCN3 Protein (His Tag)
- Sequence
- Met1-Leu328
- Characteristics
- A DNA sequence encoding the mouse Rcn3 (NP_080831.2) (Met1-Leu328) was expressed with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product RCN3 Protein
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Reticulocalbin 3, EF-Hand Calcium Binding Domain (RCN3) (AA 21-328) protein (His tag)
RCN3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Reticulocalbin 3, EF-Hand Calcium Binding Domain (RCN3) protein (Myc-DYKDDDDK Tag)RCN3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- RCN3 (Reticulocalbin 3, EF-Hand Calcium Binding Domain (RCN3))
- Alternative Name
- Reticulocalbin 3/RCN3 (RCN3 Products)
- Synonyms
- RLP49 Protein, 6030455P07Rik Protein, D530026G20Rik Protein, D7Ertd671e Protein, reticulocalbin 3 Protein, reticulocalbin 3, EF-hand calcium binding domain Protein, RCN3 Protein, Rcn3 Protein
- Background
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Background: RCN3 belongs to the CREC family which contains multiple EF-hand Ca2+-binding proteins localized to the secretory pathway. RCN3 sequence is characterized by the presence of five Arg-Xaa-Xaa-Arg motifs, which represents the target sequence of subtilisin-like proprotein convertases(SPCs). SPCs are a family of seven structurally related serine endoproteases that are involved in the proteolytic activation of proproteins.RCN3 is transiently associated with proPACE4, but not with mature PACE4. Inhibition of PACE4 maturation by a Ca2+ ionophore resulted in accumulation of the proPACE4-RCN-3 complex in cells. It has been proposed that elective and transient association of RCN3 with the precursor of PACE4 plays an important role in the biosynthesis of PACE4.
Synonym: 6030455P07Rik,D530026G20Rik,D7Ertd671e,RLP49
- Molecular Weight
- 36.9 kDa
- NCBI Accession
- NP_080831
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