RTN4R Protein (His tag)
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- Target See all RTN4R Proteins
- RTN4R (Reticulon 4 Receptor (RTN4R))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This RTN4R protein is labelled with His tag.
- Purpose
- Recombinant Human Nogo Receptor/NgR Protein (His Tag)
- Sequence
- Cys27-Ser447
- Characteristics
- Recombinant Human Nogo-66 Receptor/Reticulon 4 Receptor is produced by our Mammalian expression system and the target gene encoding Cys27-Ser447 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product RTN4R Protein
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Reticulon 4 Receptor (RTN4R) (AA 1-473) protein (GST tag)
RTN4R Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Reticulon 4 Receptor (RTN4R) (Active) protein (His tag)RTN4R Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Reticulon 4 Receptor (RTN4R) (Active) protein (His tag,Fc Tag)RTN4R Origin: Mouse Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Reticulon 4 Receptor (RTN4R) (AA 27-447) protein (His tag)Crystallography grade RTN4R Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Reticulon 4 Receptor (RTN4R) (AA 27-447) protein (His tag)Crystallography grade RTN4R Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- RTN4R (Reticulon 4 Receptor (RTN4R))
- Alternative Name
- Nogo Receptor/NgR (RTN4R Products)
- Synonyms
- NgR Protein, NGR Protein, NOGOR Protein, NgR1 Protein, Nogor Protein, reticulon 4 receptor Protein, rtn4r Protein, RTN4R Protein, Rtn4r Protein
- Background
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Background: Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be proposed as a potential drug target for treatment of various neurological conditions. Additionally, NgR may play a role in regulating the function of gap junctions.
Synonym: Reticulon-4 Receptor, Nogo Receptor, NgR, Nogo-66 Receptor, RTN4R, NOGOR
- Molecular Weight
- 46.3 kDa
- UniProt
- Q9BZR6
- Pathways
- Neurotrophin Signaling Pathway
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