RGMA Protein (His tag)
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- Target See all RGMA Proteins
- RGMA (RGM Domain Family, Member A (RGMA))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RGMA protein is labelled with His tag.
- Purpose
- Recombinant Human RGMA Protein (HEK293 Cells, His Tag)
- Sequence
- Met 1-Gly 422
- Characteristics
- A DNA sequence encoding the human RGMA isoform 3 (NP_064596.2) (Met 1-Gly 422), without the C-terminal pro peptide, was fused with a polyhistidine tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product RGMA Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- RGMA (RGM Domain Family, Member A (RGMA))
- Alternative Name
- RGMA (RGMA Products)
- Synonyms
- RGM Protein, BC059072 Protein, C230063O06 Protein, repulsive guidance molecule family member a Protein, repulsive guidance molecule family member A Protein, RGMA Protein, Rgma Protein
- Background
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Background: RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.
Synonym: Repulsive guidance molecule A,RGM domain family member A,RGM
- Molecular Weight
- 43 kDa
- NCBI Accession
- NP_064596
- Pathways
- Tube Formation
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