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RGMA Protein (His tag)

RGMA Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317418
  • Target See all RGMA Proteins
    RGMA (RGM Domain Family, Member A (RGMA))
    Protein Type
    Recombinant
    Origin
    • 8
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This RGMA protein is labelled with His tag.
    Purpose
    Recombinant Human RGMA Protein (HEK293 Cells, His Tag)
    Sequence
    Met 1-Gly 422
    Characteristics
    A DNA sequence encoding the human RGMA isoform 3 (NP_064596.2) (Met 1-Gly 422), without the C-terminal pro peptide, was fused with a polyhistidine tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product RGMA Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    RGMA (RGM Domain Family, Member A (RGMA))
    Alternative Name
    RGMA (RGMA Products)
    Synonyms
    RGM Protein, BC059072 Protein, C230063O06 Protein, repulsive guidance molecule family member a Protein, repulsive guidance molecule family member A Protein, RGMA Protein, Rgma Protein
    Background

    Background: RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.

    Synonym: Repulsive guidance molecule A,RGM domain family member A,RGM

    Molecular Weight
    43 kDa
    NCBI Accession
    NP_064596
    Pathways
    Tube Formation
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