SELPLG Protein (Fc Tag)
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- Target See all SELPLG Proteins
- SELPLG (Selectin P Ligand (SELPLG))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This SELPLG protein is labelled with Fc Tag.
- Purpose
- Recombinant Human PSGL-1/CD162 Protein (Fc Tag)
- Sequence
- Thr44-Gly295
- Characteristics
- Recombinant Human PSGL-1 is produced by our Mammalian expression system and the target gene encoding Thr44-Gly295 is expressed with a Fc tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SELPLG Protein
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Selectin P Ligand (SELPLG) (AA 42-307) protein (His tag)
SELPLG Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin P Ligand (SELPLG) (AA 34-356) protein (His tag)SELPLG Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin P Ligand (SELPLG) (AA 42-320) protein (His tag)SELPLG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Selectin P Ligand (SELPLG) (AA 18-320) protein (His tag)SELPLG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Selectin P Ligand (SELPLG) protein (Fc Tag)SELPLG Origin: Mouse Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- SELPLG (Selectin P Ligand (SELPLG))
- Alternative Name
- PSGL-1/CD162 (SELPLG Products)
- Synonyms
- CD162 Protein, CLA Protein, PSGL-1 Protein, PSGL1 Protein, SELPLG Protein, SELPG Protein, Psgl-1 Protein, Psgl1 Protein, Selp1 Protein, Selpl Protein, selectin P ligand Protein, selectin, platelet (p-selectin) ligand Protein, clasper Protein, SELPLG Protein, Selplg Protein, cla Protein
- Background
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Background: PSGL-1 (CD162), is a mucintype glycoprotein that plays a key role in leukocyte adhesion. Human PSGL-1 cDNA encodes 412 amino acids (aa). It expressed on neutrophils, monocytes and most lymphocytes. The mature PSGL-1 (aa 42-412) is expressed as a disulfide-linked homodimer that signals intracellularly and promotes integrin activation. PSGL-1 is found on virtually all leukocytes, dendritic cells, platelets, and some endothelial cells. It is primarily responsible for early events in extravasation, especially rolling adhesion of leukocytes to vascular endothelium. Through high affinity, This SLe(x)-type proteoglycanPGSL-1 calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation.
Synonym: P-selectin glycoprotein ligand 1, PSGL-1, Selectin P ligand, CD162, SELPLG,CLA,PSGL1
- Molecular Weight
- 52.7 kDa
- UniProt
- Q14242
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