SERPINB5 Protein
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- Target See all SERPINB5 Proteins
- SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human SerpinB5/SERPINB5 Protein
- Sequence
- Met 1-Ser231
- Characteristics
- Recombinant Human Serine Protease Inhibitor-clade B5 is produced by our E.coli expression system and the target gene encoding Met1-Ser231 is expressed.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SERPINB5 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))
- Alternative Name
- SerpinB5/SERPINB5 (SERPINB5 Products)
- Synonyms
- 1110036M19Rik Protein, AI462524 Protein, AI646751 Protein, Maspin Protein, PI-5 Protein, Spi7 Protein, ovalbumin Protein, PI5 Protein, maspin Protein, Pi5 Protein, serine (or cysteine) peptidase inhibitor, clade B, member 5 Protein, serpin family B member 5 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 5 S homeolog Protein, Serpinb5 Protein, SERPINB5 Protein, serpinb5.S Protein
- Background
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Background: Serpin B5 is a secretive protein that belongs to the Serpin (Serine Protease Inhibitor) family and Ov-serpin subfamily. Serpin B5 is expressed in the prostate, testis, intestine, tongue, lung, and thymus. Serpin B5 exhibits no serine protease inhibitory activity. Serpin B5 also functions as tumor suppressor an angiogenesis inhibitor. It has been shown that Serpin B5 blocks the growth, invasion, and metastatic properties of mammary tumors. Furthermore, high expression of Serpin B5 is linked to squamous cell carcinoma in non-small-cell lung cancer.
Synonym: Serpin B5, Maspin, Peptidase Inhibitor 5, PI-5, SERPINB5, PI5
- Molecular Weight
- 25.7 kDa
- Pathways
- p53 Signaling
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