SPOCK1 Protein (AA 21-429) (His tag)
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- Target See all SPOCK1 Proteins
- SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-429
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This SPOCK1 protein is labelled with His tag.
- Purpose
- Recombinant Human SPOCK1/Testican 1 Protein (aa 21-429, His Tag)
- Sequence
- Met 1-Trp439
- Characteristics
- A DNA sequence encoding the human SPOCK1 (Q08629) ( Met 1-Trp439) was expressed with a C-terminal polyhistidine tag.
- Purity
- > 85 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SPOCK1 Protein
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Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1) (AA 1-439) protein (GST tag)
SPOCK1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1) (AA 22-439) protein (His tag)Crystallography grade SPOCK1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1) (AA 22-442) protein (His tag)Crystallography grade SPOCK1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))
- Alternative Name
- SPOCK1/Testican 1 (SPOCK1 Products)
- Synonyms
- SPOCK Protein, TESTICAN Protein, TIC1 Protein, Spock Protein, Ticn1 Protein, testican Protein, SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1 Protein, sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 Protein, sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 Protein, SPOCK1 Protein, Spock1 Protein
- Background
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Background: Osteonectin, also known as SPOCK1, is an extracellular heparan/chondroitin sulfate proteoglycan. Members of this family are known as testicans, also called SPOCKs. They are characterized structurally by an N-terminal testican-specific domain, a follistatin-like region, a calcium-binding domain, a thyroglobulin-like domain, and an acidic C-terminal domain with two putative glycosaminoglycan attachment sites. SPOCKs are enriched in brain and have been shown to regulate neuronal attachment and outgrowth. They contain inhibitory regions in several domains targeted to different classes of protease, and in some cases may act as protease inhibitors. Osteonectin contains 1 Kazal-like domain and 1 thyroglobulin type-1 domain. Up to now, little is known about osteonectin's function. It may play a role in cell-cell and cell-matrix interactions. Osteonectin also may contribute to various neuronal mechanisms in the central nervous system.
Synonym: SPOCK,TESTICAN,TIC1
- Molecular Weight
- 48.4 kDa
- UniProt
- Q08629
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