SDF2 Protein (His tag)

Catalog No. ABIN7198125

Product Details

Target: SDF2 (Stromal Cell Derived Factor 2 (SDF2))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This SDF2 protein is labelled with His tag.

Purpose: Recombinant Human SDF2 Protein (His Tag)

Sequence: Met 1-Leu 211

Characteristics: A DNA sequence encoding the pro form of human SDF2 (NP_008854.2) (Met 1-Leu 211) was expressed with a C-terminal polyhistidine tag.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 0.5 mM PMSF, 0.5 mM EDTA, 0.5 mM TCEP, 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SDF2 (Stromal Cell Derived Factor 2 (SDF2))

Alternative Name: SDF2 (SDF2 Products)

Synonyms: AI853825 Protein, fk23f01 Protein, wu:fk23f01 Protein, zgc:66291 Protein, stromal cell derived factor 2 Protein, stromal cell-derived factor 2 Protein, stromal cell derived factor 2 L homeolog Protein, sdf2 Protein, Sdf2 Protein, sdf2.L Protein, SDF2 Protein

Background:

Background: Stromal derived factors (SDFs) are a loosely defined group of molecules that are generated by stromal cells. Two of the stromal derived factors, SDF-1 and SDF-4 belong to the chemokine family. Other SDFs, such as SDF-2 and SDF-5 are not well defined and their biological functions are less known. SDF-2 is first isolated from the mouse stromal cell line ST2 as a secretory protein. The amino acid sequence deduced from the murine clone and the human homolog are conserved more than 92 %, and the aa sequence of SDF-2 shows similarity to those of yeast dolichyl phosphate-D-mannose, protein mannosyltransferases. SDF-1 and its receptor are strongly indicated in the progression of various cancers including breast cancer. SDF-2, SDF2-L1, SDF-4, and SDF-5 are ubiquitously expressed in various cancer cell lines and SDF-2, SDF-4 and SDF-5 are expressed in mammary tissues. These SDFs have prognostic value and warrant further investigation in their biological functions and clinical value.

Synonym: SDF2

Molecular Weight: 22.7 kDa

NCBI Accession: NP_008854

Pathways: SARS-CoV-2 Protein Interactome