Thimet Oligopeptidase 1 Protein (THOP1) (His tag)
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- Target See all Thimet Oligopeptidase 1 (THOP1) Proteins
- Thimet Oligopeptidase 1 (THOP1)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Thimet Oligopeptidase 1 protein is labelled with His tag.
- Purpose
- Recombinant Human THOP1 Protein (His Tag)
- Sequence
- Lys2-Cys689
- Characteristics
- Recombinant Human Thimet Oligopeptidase is produced by our E.coli expression system and the target gene encoding Lys2-Cys689 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product THOP1 Protein
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Thimet Oligopeptidase 1 (THOP1) (AA 1-689) protein (GST tag)
THOP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Thimet Oligopeptidase 1 (THOP1) (AA 255-354) protein (GST tag)THOP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Thimet Oligopeptidase 1 (THOP1) (Active) protein (His tag)THOP1 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE Active
Thimet Oligopeptidase 1 (THOP1) (AA 1-689) protein (Strep Tag)Crystallography grade THOP1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Thimet Oligopeptidase 1 (THOP1) (AA 1-687) protein (Strep Tag)Crystallography grade THOP1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Thimet Oligopeptidase 1 (THOP1) protein (Myc-DYKDDDDK Tag)THOP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 100 mM NaCl, 10 % Glycerol, pH 7.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- Thimet Oligopeptidase 1 (THOP1)
- Alternative Name
- THOP1 (THOP1 Products)
- Synonyms
- EP24.15 Protein, MEPD_HUMAN Protein, MP78 Protein, TOP Protein, AI131655 Protein, AI327041 Protein, THOP1 Protein, thop1 Protein, MGC147297 Protein, LOC397806 Protein, mepd Protein, thimet oligopeptidase 1 Protein, thimet oligopeptidase 1 L homeolog Protein, thimet oligopeptidase Protein, peptidase Protein, Thimet oligopeptidase Protein, THOP1 Protein, Thop1 Protein, thop1 Protein, thop1.L Protein, Tc00.1047053506411.10 Protein, Tc00.1047053511237.10 Protein, Noca_4613 Protein, ANI_1_1400064 Protein, MBOO_RS10705 Protein, AOR_1_880174 Protein, AnaeK_0425 Protein, MPAL_RS03920 Protein, Hoch_5061 Protein, mepd Protein
- Background
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Background: Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase. THOP1 is located in Cytoplasm. THOP1 is widely expressed in human tissues and can detected in different subcellular locations. THOP1 is preferential cleavage for bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues. THOP1 is involved in the metabolism of neuropeptides under 20 amino acid residues and degradation of cytoplasmic peptide. In addition, THOP1 also can degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.
Synonym: Thimet Oligopeptidase, Endopeptidase 24.15, MP78, THOP1
- Molecular Weight
- 80.0 kDa
- UniProt
- P52888
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