TRIM5 Protein (His tag)
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- Target See all TRIM5 Proteins
- TRIM5 (Tripartite Motif Containing 5 (TRIM5))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TRIM5 protein is labelled with His tag.
- Purpose
- Recombinant Human TRIM5/RNF88 Protein (His Tag)
- Sequence
- Met 1-Gln248
- Characteristics
- Recombinant Human Tripartite motif-containing protein 5 is produced by our E.coli expression system and the target gene encoding Met1-Gln248 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TRIM5 Protein
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Tripartite Motif Containing 5 (TRIM5) (AA 309-418) protein (GST tag)
TRIM5 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Tripartite Motif Containing 5 (TRIM5) (AA 1-347) protein (GST tag)TRIM5 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Tripartite Motif Containing 5 (TRIM5) proteinTRIM5 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant ELISA, WB, SDS, IP
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- TRIM5 (Tripartite Motif Containing 5 (TRIM5))
- Alternative Name
- TRIM5/RNF88 (TRIM5 Products)
- Synonyms
- TRIM5 Protein, RNF88 Protein, TRIM5alpha Protein, EG667823 Protein, Gm8833 Protein, RGD1304579 Protein, tripartite motif containing 5 Protein, tripartite motif-containing 5 Protein, TRIM5 Protein, Trim5 Protein
- Background
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Background: Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognizes motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of action has not been shown conclusively, but capsid protein from restricted viruses is removed by proteasome-dependent degradation
Synonym: Tripartite motif-containing protein 5,RING finger protein 88,TRIM5,RNF88
- Molecular Weight
- 30.8 kDa
- UniProt
- Q9C035
- Pathways
- Activation of Innate immune Response
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