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TPSB2 Protein (His tag)

TPSB2 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319120
  • Target See all TPSB2 Proteins
    TPSB2 (Tryptase beta 2 (TPSB2))
    Protein Type
    Recombinant
    Origin
    • 5
    • 4
    • 2
    Human
    Source
    • 5
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This TPSB2 protein is labelled with His tag.
    Purpose
    Recombinant Human Tryptase β-2/TPSB2 Protein (His Tag)
    Sequence
    Ala19-Pro275
    Characteristics
    Recombinant Human Tryptase beta-2 is produced by our Mammalian expression system and the target gene encoding Ala19-Pro275 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product TPSB2 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    TPSB2 (Tryptase beta 2 (TPSB2))
    Alternative Name
    Tryptase beta-2/TPSB2 (TPSB2 Products)
    Synonyms
    TPS2 Protein, tryptaseB Protein, tryptaseC Protein, Mcpt6 Protein, tryptase beta 2 (gene/pseudogene) Protein, tryptase beta 2 Protein, TPSB2 Protein, Tpsb2 Protein
    Background

    Background: Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.

    Synonym: Tryptase Beta-2, Tryptase-2, Tryptase II, TPSB2, TPS2

    Molecular Weight
    29.6 kDa
    UniProt
    P20231
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