TPSB2 Protein (AA 19-275) (His tag)
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- Target See all TPSB2 Proteins
- TPSB2 (Tryptase beta 2 (TPSB2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-275
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This TPSB2 protein is labelled with His tag.
- Purpose
- Recombinant Human Tryptase β-2/TPSB2 (C-6His)
- Sequence
- APAPGQALQR VGIVGGQEAP RSKWPWQVSL RVHGPYWMHF CGGSLIHPQW VLTAAHCVGP DVKDLAALRV QLREQHLYYQ DQLLPVSRII VHPQFYTAQI GADIALLELE EPVKVSSHVH TVTLPPASET FPPGMPCWVT GWGDVDNDER LPPPFPLKQV KVPIMENHIC DAKYHLGAYT GDDVRIVRDD MLCAGNTRRD SCQGDSGGPL VCKVNGTWLQ AGVVSWGEGC AQPNRPGIYT RVTYYLDWIH HYVPKKPVDH HHHHH
- Characteristics
- Recombinant Human Tryptase β-2/TPSB2 produced by transfected human cells is a secreted protein with sequence (Ala19-Pro275) of Human TPSB2 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product TPSB2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- TPSB2 (Tryptase beta 2 (TPSB2))
- Alternative Name
- Tryptase beta-2/TPSB2 (TPSB2 Products)
- Synonyms
- TPS2 Protein, tryptaseB Protein, tryptaseC Protein, Mcpt6 Protein, tryptase beta 2 (gene/pseudogene) Protein, tryptase beta 2 Protein, TPSB2 Protein, Tpsb2 Protein
- Background
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Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.
Synonyms: Tryptase Beta-2, Tryptase-2, Tryptase II, TPSB2, TPS2 - Molecular Weight
- 29.64 kDa
- UniProt
- P20231
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