UBE2C Protein (His tag)
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- Target See all UBE2C Proteins
- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UBE2C protein is labelled with His tag.
- Purpose
- Recombinant Human UBE2C Protein (His Tag)
- Sequence
- Met 1-Pro179
- Characteristics
- Recombinant Human Ubiquitin-Conjugating Enzyme E2 C is produced by our E.coli expression system and the target gene encoding Met1-Pro179 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product UBE2C Protein
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Ubiquitin-Conjugating Enzyme E2C (UBE2C) (AA 1-179) protein (His tag)
UBE2C Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (AA 1-179) protein (GST tag)UBE2C Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (AA 70-179) protein (GST tag)UBE2C Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (AA 25-129) protein (GST tag)UBE2C Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)UBE2C Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)UBE2C Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (Transcript Variant 5) protein (Myc-DYKDDDDK Tag)UBE2C Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
- Alternative Name
- UBE2C (UBE2C Products)
- Synonyms
- LOC458287 Protein, UBCH10 Protein, dJ447F3.2 Protein, 1110015A16Rik Protein, D2Ertd695e Protein, im:7137135 Protein, zgc:123190 Protein, ubiquitin conjugating enzyme E2 C Protein, ubiquitin-conjugating enzyme E2C Protein, ubiquitin conjugating enzyme E2 C L homeolog Protein, ubiquitin conjugating enzyme E2 C S homeolog Protein, UBE2C Protein, NAEGRDRAFT_82946 Protein, ube2c.L Protein, Ube2c Protein, ube2c.S Protein, ube2c Protein
- Background
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Background: Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a 179 amino acid enzyme that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2C is highly expressed in tumor tissues and at low levels in most adult normal tissues. UBE2C is required for the destruction of mitotic cyclins and for cell cycle progression. UBE2C accepts Ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), which has E3 ubiquitin ligase activity, and targets for destruction substrates from the preceding mitosis (Cyclin A, Cyclin B, Securin, Geminin).
Synonym: Ubiquitin-Conjugating Enzyme E2 C, UbcH10, Ubiquitin Carrier Protein C, Ubiquitin-Protein Ligase C, UBE2C, UBCH10
- Molecular Weight
- 23.3 kDa
- UniProt
- O00762
- Pathways
- Ubiquitin Proteasome Pathway
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