UBE2D1 Protein (His tag)
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- Target See all UBE2D1 Proteins
- UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UBE2D1 protein is labelled with His tag.
- Purpose
- Recombinant Human UBE2D1 Protein (His Tag)
- Sequence
- Ala 2-Met 147
- Characteristics
- A DNA sequence encoding the human UBE2D1 (P51668) (Ala 2-Met 147) was expressed, with a polyhistide tag at the N-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product UBE2D1 Protein
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Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (AA 1-147) protein (His-IF2DI Tag)
UBE2D1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (AA 1-147) protein (GST tag)UBE2D1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (AA 1-94) protein (GST tag)UBE2D1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (AA 1-147) protein (Strep Tag)Crystallography grade UBE2D1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) protein (Myc-DYKDDDDK Tag)UBE2D1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 25 mM Tris, 100 mM NaCl, 20 % glycerol, 0.05 % Tween
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
- Alternative Name
- UBE2D1 (UBE2D1 Products)
- Synonyms
- E2(17)KB1 Protein, SFT Protein, UBC4/5 Protein, UBCH5 Protein, UBCH5A Protein, ube2d1 Protein, wu:fc16h06 Protein, zgc:73096 Protein, e2(17)kb1 Protein, sft Protein, ubc4/5 Protein, ubch5 Protein, ubch5a Protein, ubiquitin conjugating enzyme E2 D1 Protein, ubiquitin-conjugating enzyme E2D 1 Protein, ubiquitin-conjugating enzyme E2D 1b Protein, ubiquitin conjugating enzyme E2 D1 S homeolog Protein, UBE2D1 Protein, Ube2d1 Protein, ube2d1b Protein, ube2d1.S Protein, ube2d1 Protein
- Background
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Background: Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis, as previously published for SFT. Moreover, a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells.
Synonym: Ubiquitin-conjugating enzyme E2 D1,Stimulator of Fe transport,SFT,UBC4/5 homolog,UbcH5,Ubiquitin carrier protein D1,Ubiquitin-conjugating enzyme E2(17)KB 1,Ubiquitin-conjugating enzyme E2-17 kDa 1,Ubiquitin-protein ligase D1,SFT, UBC5A, UBCH5, UBCH5A
- Molecular Weight
- 18.3 kDa
- UniProt
- P51668
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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