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VEGFB Protein (Fc Tag)

VEGFB Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319412
  • Target See all VEGFB Proteins
    VEGFB (Vascular Endothelial Growth Factor B (VEGFB))
    Protein Type
    Recombinant
    Origin
    • 10
    • 3
    • 3
    • 1
    • 1
    Human
    Source
    • 9
    • 3
    • 2
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This VEGFB protein is labelled with Fc Tag.
    Purpose
    Recombinant Human VEGF-B/VEGFB Protein (Fc Tag)
    Sequence
    Pro22-Ala207
    Characteristics
    Recombinant Human VEGFB is produced by our Mammalian expression system and the target gene encoding Pro22-Ala207 is expressed with a Fc tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product VEGFB Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    VEGFB (Vascular Endothelial Growth Factor B (VEGFB))
    Alternative Name
    VEGF-B/VEGFB (VEGFB Products)
    Synonyms
    VEGFL Protein, VRF Protein, VEGF-B Protein, Vrf Protein, vascular endothelial growth factor B Protein, VEGFB Protein, Vegfb Protein
    Background

    Background: VEGFB, as known as VRF, is a member of the VEGF family of growth factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane receptor for semaphorins/collapsins, ligands involved in neuron guidance.

    Synonym: Vascular endothelial growth factor B,VEGF-B,VEGF-related factor,VRF

    Molecular Weight
    45.7 kDa
    UniProt
    P49765
    Pathways
    RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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