CD47 Protein (CD47) (Fc Tag)
Quick Overview for CD47 Protein (CD47) (Fc Tag) (ABIN7321002)
Target
See all CD47 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD47 protein is labelled with Fc Tag.
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Purpose
- Recombinant Rhesus macaque CD47/IAP Protein (Fc Tag)
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Sequence
- Gln19-Pro139
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Characteristics
- Recombinant Rhesus macaque CD47 is produced by our Mammalian expression system and the target gene encoding Gln19-Pro139 is expressed with a Fc tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Comment
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60-90 kDa
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH 7.5.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD47
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Alternative Name
- CD47/IAP
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Background
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Background: CD47(Integrin-Associated Protein,IAP) is a 40 ? 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
Synonym: Leukocyte Surface Antigen CD47, Antigenic Surface Determinant Protein OA3, Integrin-Associated Protein, IAP, Protein MER6, CD47, MER6
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Molecular Weight
- 40.8 kDa
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UniProt
- F7A802
Target
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