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CD47 Protein (CD47) (Fc Tag)

This Recombinant CD47 protein is expressed in Human Cells.
Catalog No. ABIN7321002
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Quick Overview for CD47 Protein (CD47) (Fc Tag) (ABIN7321002)

Target

See all CD47 Proteins
CD47

Protein Type

Recombinant

Origin

  • 38
  • 16
  • 8
  • 5
  • 4
  • 2
  • 2
  • 1
Rhesus Monkey

Source

  • 42
  • 8
  • 7
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This CD47 protein is labelled with Fc Tag.

    Purpose

    Recombinant Rhesus macaque CD47/IAP Protein (Fc Tag)

    Sequence

    Gln19-Pro139

    Characteristics

    Recombinant Rhesus macaque CD47 is produced by our Mammalian expression system and the target gene encoding Gln19-Pro139 is expressed with a Fc tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Comment

    60-90 kDa

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH 7.5.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CD47

    Alternative Name

    CD47/IAP

    Background

    Background: CD47(Integrin-Associated Protein,IAP) is a 40 ? 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.

    Synonym: Leukocyte Surface Antigen CD47, Antigenic Surface Determinant Protein OA3, Integrin-Associated Protein, IAP, Protein MER6, CD47, MER6

    Molecular Weight

    40.8 kDa

    UniProt

    F7A802
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