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CD47 Protein (CD47) (Fc Tag)

This Recombinant CD47 protein is expressed in Human Cells.
Catalog No. ABIN7321002

Quick Overview for CD47 Protein (CD47) (Fc Tag) (ABIN7321002)

Target

See all CD47 Proteins
CD47

Protein Type

Recombinant

Origin

  • 36
  • 15
  • 6
  • 5
  • 4
  • 2
  • 1
Rhesus Monkey

Source

  • 42
  • 7
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This CD47 protein is labelled with Fc Tag.

    Purpose

    Recombinant Rhesus macaque CD47/IAP Protein (Fc Tag)

    Sequence

    Gln19-Pro139

    Characteristics

    Recombinant Rhesus macaque CD47 is produced by our Mammalian expression system and the target gene encoding Gln19-Pro139 is expressed with a Fc tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Comment

    60-90 kDa

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH 7.5.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CD47

    Alternative Name

    CD47/IAP

    Background

    Background: CD47(Integrin-Associated Protein,IAP) is a 40 ? 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.

    Synonym: Leukocyte Surface Antigen CD47, Antigenic Surface Determinant Protein OA3, Integrin-Associated Protein, IAP, Protein MER6, CD47, MER6

    Molecular Weight

    40.8 kDa

    UniProt

    F7A802
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