ACVA Protein (AA 311-426)
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- Target See all ACVA Proteins
- ACVA (Activin A (ACVA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 311-426
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human Activin A Protein
- Sequence
- Gly311-Ser426
- Characteristics
- Recombinant Human Activin A Protein is expressed from HEK293 without tag.It contains Gly311-Ser426.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product ACVA Protein
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Activin A (ACVA) (AA 311-426) (Active) protein
ACVA Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Activin A (ACVA) (AA 309-424) protein (His tag)ACVA Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Activin A (ACVA) (AA 309-424) protein (His tag)ACVA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Activin A (ACVA) (AA 21-426) (Active) protein (His tag)ACVA Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 4 mM HCI.
- Buffer
- Lyophilized from 0.22μm filtered solution in 4 mM HCI. Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- ACVA (Activin A (ACVA))
- Alternative Name
- Activin A (ACVA Products)
- Synonyms
- inhibin beta A subunit Protein, Inhba Protein
- Background
- Activin-A, a member of the TGF-β superfamily, Extensive research over the past decades illuminated fundamental roles for activin-A in essential biologic processes, including embryonic development, stem cell maintenance and differentiation, haematopoiesis, cell proliferation and tissue fibrosis. Activin-A signals through two type I and two type II receptors which, upon ligand binding, activate their kinase activity, phosphorylate the SMAD2 and 3 intracellular signaling mediators that form a complex with SMAD4, translocate to the nucleus and activate or silence gene expression.
- Molecular Weight
- 12.97 kDa. Due to glycosylation, the protein migrates to 14-15 kDa under reduced (R) condition, and 23-25 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.
- UniProt
- P08476
- Pathways
- Hormone Transport, Peptide Hormone Metabolism
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