alpha Fetoprotein Protein (AA 19-605) (His tag)
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- Target See all alpha Fetoprotein (AFP) Proteins
- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-605
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This alpha Fetoprotein protein is labelled with His tag.
- Purpose
- Mouse AFP Protein
- Sequence
- Lys19-Val605
- Characteristics
- Recombinant Mouse AFP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys19-Val605.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
- Alternative Name
- AFP (AFP Products)
- Synonyms
- FETA Protein, HPAFP Protein, alpha fetoprotein Protein, alpha-fetoprotein Protein, AFP Protein, Afp Protein
- Background
- Alpha-fetoprotein is a shuttle protein that delivers nutrients through receptor-mediated endocytosis to embryotic cells. In adults, alpha-fetoprotein can shuttle drugs into alpha-fetoprotein receptor-positive myeloid-derived suppressor, regenerating and also cancer cells. Drugs with high-binding affinity to alpha-fetoprotein can activate or deplete targeted cells. Myeloid-derived suppressor cells activation leads to immune suppression that can be used for treating autoimmune diseases.
- Molecular Weight
- 66.40 kDa. Due to glycosylation, the protein migrates to 68-72 kDa based on Tris-Bis PAGE result.
- UniProt
- P02772
- Pathways
- C21-Steroid Hormone Metabolic Process
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