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Apelin Protein (APLN) (AA 23-77) (Fc Tag)

APLN Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7273863
  • Target See all Apelin (APLN) Proteins
    Apelin (APLN)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 23-77
    Origin
    • 6
    • 3
    • 2
    Mouse
    Source
    • 6
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Apelin protein is labelled with Fc Tag.
    Purpose
    Mouse APLN Protein
    Sequence
    Val23-Phe77
    Characteristics
    Recombinant Mouse APLN Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Val23-Phe77.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS, 200 mM Arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Apelin (APLN)
    Alternative Name
    APLN (APLN Products)
    Synonyms
    APLN Protein, Xapelin Protein, xnpep2 Protein, preproapelin Protein, 6030430G11Rik Protein, Apel Protein, APEL Protein, XNPEP2 Protein, apelin Protein, apelin S homeolog Protein, apln Protein, APLN Protein, apln.S Protein, Apln Protein
    Background
    Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized that APLN may perform its roles via modulation of macrophages. Additionally, due to the widespread distribution of the CVD, more effective therapeutic strategies need to be developed to overcome the related complications.
    Molecular Weight
    33 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
    UniProt
    Q9R0R4
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Feeding Behaviour
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