beta-2 Microglobulin Protein (AA 21-119) (Fc Tag)
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- Target See all beta-2 Microglobulin (B2M) Proteins
- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-119
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This beta-2 Microglobulin protein is labelled with Fc Tag.
- Purpose
- Human B2M/beta 2-Microglobulin Protein
- Sequence
- Ile21-Met119
- Characteristics
- Recombinant Human B2M/beta 2-Microglobulin Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile21-Met119.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product B2M Protein
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beta-2-Microglobulin (B2M) (AA 21-119) protein (His tag)
B2M Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
beta-2-Microglobulin (B2M) (AA 21-119) protein (His tag)B2M Origin: Rhesus Monkey, Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
beta-2-Microglobulin (B2M) (AA 21-119) protein (Fc Tag)B2M Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
beta-2-Microglobulin (B2M) (AA 1-119) protein (GST tag)B2M Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
beta-2-Microglobulin (B2M) (AA 21-119) protein (His tag)Crystallography grade B2M Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
- Alternative Name
- B2M (B2M Products)
- Synonyms
- Ly-m11 Protein, beta2-m Protein, beta2m Protein, bwm Protein, wu:fa94c05 Protein, wu:fb10a09 Protein, b2m-W01 Protein, b2m-W03 Protein, b2m-Z01 Protein, b2m-Z02 Protein, b2m-Z03 Protein, B2M Protein, b2m Protein, B2MG Protein, wu:fb66f11 Protein, wu:fj01f08 Protein, zgc:64161 Protein, b-2-m Protein, beta-2-microglobulin Protein, beta-2 microglobulin Protein, beta-2-microglobulin S homeolog Protein, beta-2-microglobulin, like Protein, B2M Protein, B2m Protein, b2m Protein, b2m.S Protein, b2ml Protein
- Background
- To assess whether beta-2 microglobulin (B2M) has effects on articular chondrocytes that would implicate B2M involvement in osteoarthritis (OA) pathogenesis.The average B2M level in OA synovial fluid is significantly higher than that found in normal synovial fluid. B2M is highly expressed in OA cartilage and synovial fluid compared to normal, and suggest that B2M may have effects on chondrocyte function that could contribute to OA pathogenesis.
- Molecular Weight
- 38.4 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
- Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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