CD24 Protein (AA 27-59) (mFc Tag)

Catalog No. ABIN7274115

Product Details

Target: CD24 (CD24 Molecule (CD24))

Protein Type: Recombinant

Protein Characteristics: AA 27-59

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CD24 protein is labelled with mFc Tag.

Purpose: Human CD24 Protein

Sequence: Ser27-Gly59

Characteristics: Recombinant Human CD24 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Ser27-Gly59.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human CD24, mFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-CD24 Antibody, hFc Tag with the EC50 of 0.19μg/ml determined by ELISA. See testing image for detail.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: CD24 (CD24 Molecule (CD24))

Alternative Name: CD24 (CD24 Products)

Synonyms: CD24A Protein, Cd24a Protein, CD24 molecule Protein, CD24 Protein, Cd24 Protein

Background: CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers.

Molecular Weight: 29.5 kDa. Due to glycosylation, the protein migrates to 48-60 kDa based on Tris-Bis PAGE result.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation