CD37 Protein (AA 113-240) (Fc Tag)
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- Target See all CD37 (TSPAN26) Proteins
- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 113-240
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD37 protein is labelled with Fc Tag.
- Purpose
- Human CD37 Protein
- Sequence
- Ala113-Asn240
- Characteristics
- Recombinant Human CD37 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ala113-Asn240.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Tetraspanin 26 (TSPAN26) (AA 112-211) protein (GST tag)
TSPAN26 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Tetraspanin 26 (TSPAN26) (AA 112-241) protein (His tag)Crystallography grade TSPAN26 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Tetraspanin 26 (TSPAN26) (AA 112-241) protein (His tag)Crystallography grade TSPAN26 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Tetraspanin 26 (TSPAN26) (AA 1-281) protein (Strep Tag)Crystallography grade TSPAN26 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Tetraspanin 26 (TSPAN26) (AA 1-281) protein (Strep Tag)Crystallography grade TSPAN26 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Tetraspanin 26 (TSPAN26) (AA 112-241) protein (His tag)TSPAN26 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
- Alternative Name
- CD37 (TSPAN26 Products)
- Synonyms
- Tspan26 Protein, GP52-40 Protein, TSPAN26 Protein, CD37 antigen Protein, CD37 molecule Protein, Cd37 Protein, CD37 Protein
- Background
- CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and targeting this molecule may provide additional benefit to relapsed or refractory patients.
- Molecular Weight
- 41.9 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
- Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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