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CD37 Protein (AA 113-240) (His tag)

TSPAN26 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Catalog No. ABIN7504265
  • Target See all CD37 (TSPAN26) Proteins
    CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 113-240
    Origin
    • 9
    • 2
    Human
    Source
    • 4
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD37 protein is labelled with His tag.
    Purpose
    Human CD37 Protein
    Sequence
    Ala113-Asn240
    Characteristics
    Recombinant Human CD37 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala113-Asn240.
    Purity
    > 95 % as determined by Tris-Bis PAGE
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product TSPAN26 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
    Alternative Name
    CD37 (TSPAN26 Products)
    Synonyms
    Tspan26 Protein, GP52-40 Protein, TSPAN26 Protein, CD37 antigen Protein, CD37 molecule Protein, Cd37 Protein, CD37 Protein
    Background
    CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and targeting this molecule may provide additional benefit to relapsed or refractory patients.
    Molecular Weight
    15.72 kDa. Due to glycosylation, the protein migrates to 25-40 kDa based on Tris-Bis PAGE result.
    Pathways
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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