IREM1 Protein (AA 20-156) (Fc Tag)
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- Target See all IREM1 Proteins
- IREM1 (Immune Receptor Expressed On Myeloid Cells 1 (IREM1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-156
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IREM1 protein is labelled with Fc Tag.
- Purpose
- Human CD300LF Protein
- Sequence
- Thr20-Ser156
- Characteristics
- Recombinant Human CD300LF Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Thr20-Ser156.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IREM1 (Immune Receptor Expressed On Myeloid Cells 1 (IREM1))
- Alternative Name
- CD300LF (IREM1 Products)
- Synonyms
- CLIM1 Protein, CLM-1 Protein, CLM1 Protein, Digr2 Protein, F730004D16Rik Protein, IREM1 Protein, IgSF13 Protein, LMIR3 Protein, Pigr3 Protein, CD300f Protein, RGD1309733 Protein, IREM-1 Protein, NKIR Protein, CD300 molecule like family member F Protein, Cd300 molecule-like family member F Protein, CD300 molecule like family member f Protein, Cd300lf Protein, CD300LF Protein
- Background
- Murine norovirus (MNoV) is an important model of human norovirus (HNoV) and mucosal virus infection more broadly. CD300lf as a proteinaceous receptor for MNoV. Interestingly, its paralogue CD300ld was also sufficient for MNoV infection in vitro. CD300lf is essential for both oral and parenteral MNoV infection and to elicit anti-MNoV humoral responses in vivo. human CD300lf (huCD300lf) is not essential for HNoV infection, nor does huCD300lf inhibit binding of HNoV virus-like particles to glycans.
- Molecular Weight
- 42.1 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
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