CXCL13 Protein (AA 23-109) (Fc Tag)
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- Target See all CXCL13 Proteins
- CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-109
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CXCL13 protein is labelled with Fc Tag.
- Purpose
- Human CXCL13/BCA-1 Protein
- Sequence
- Val23-Per109
- Characteristics
- Recombinant Human CXCL13/BCA-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Val23-Per109.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human CXCL13, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-CXCL13 Antibody, hFc Tag with the EC50 of 17.2ng/ml determined by ELISA. See testing image for detail.
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- Discover our top product CXCL13 Protein
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Chemokine (C-X-C Motif) Ligand 13 (CXCL13) (AA 22-109) protein (Fc Tag)
CXCL13 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-X-C Motif) Ligand 13 (CXCL13) (AA 22-109) protein (His tag)CXCL13 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-X-C Motif) Ligand 13 (CXCL13) (AA 23-109) protein (His-SUMO Tag)CXCL13 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Chemokine (C-X-C Motif) Ligand 13 (CXCL13) (AA 1-109) protein (GST tag)CXCL13 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-X-C Motif) Ligand 13 (CXCL13) (AA 23-109) protein (His tag)CXCL13 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-X-C Motif) Ligand 13 (CXCL13) (AA 23-109) protein (GST tag)CXCL13 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-X-C Motif) Ligand 13 (CXCL13) (AA 22-109) protein (His tag)Crystallography grade CXCL13 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 50 mM Tris,500 mM NaCl ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
- Alternative Name
- CXCL13 (CXCL13 Products)
- Synonyms
- 4631412M08Rik Protein, ANGIE2 Protein, Angie Protein, BCA-1 Protein, BLC Protein, BLR1L Protein, Scyb13 Protein, ANGIE Protein, BCA1 Protein, SCYB13 Protein, C-X-C motif chemokine ligand 13 Protein, chemokine (C-X-C motif) ligand 13 Protein, Cxcl13 Protein, CXCL13 Protein
- Background
- Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
- Molecular Weight
- 37.6 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
- UniProt
- O43927
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