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CXCL13 Protein (AA 22-109) (Fc Tag)

CXCL13 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274450
  • Target See all CXCL13 Proteins
    CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 22-109
    Origin
    • 11
    • 5
    • 3
    • 1
    • 1
    Mouse
    Source
    • 15
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This CXCL13 protein is labelled with Fc Tag.
    Purpose
    Mouse CXCL13/BCA-1 Protein
    Sequence
    Ile22-Ala109
    Characteristics
    Recombinant Mouse CXCL13/BCA-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ile22-Ala109.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in 50 mM Tris, 500 mM NaCl ( pH 7.5).
    Storage
    -80 °C
    Storage Comment
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
    Alternative Name
    CXCL13 (CXCL13 Products)
    Synonyms
    4631412M08Rik Protein, ANGIE2 Protein, Angie Protein, BCA-1 Protein, BLC Protein, BLR1L Protein, Scyb13 Protein, ANGIE Protein, BCA1 Protein, SCYB13 Protein, C-X-C motif chemokine ligand 13 Protein, chemokine (C-X-C motif) ligand 13 Protein, Cxcl13 Protein, CXCL13 Protein
    Background
    Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
    Molecular Weight
    37.1 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
    UniProt
    O55038
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