ECSCR Protein (AA 25-124) (Fc Tag)
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- Target See all ECSCR products
- ECSCR (Endothelial Cell Surface Expressed Chemotaxis and Apoptosis Regulator (ECSCR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-124
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ECSCR protein is labelled with Fc Tag.
- Purpose
- Human ECSCR Protein
- Sequence
- Gln25-Ala124
- Characteristics
- Recombinant Human ECSCR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln25-Ala124.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- ECSCR (Endothelial Cell Surface Expressed Chemotaxis and Apoptosis Regulator (ECSCR))
- Alternative Name
- ECSCR (ECSCR Products)
- Synonyms
- ARIA Protein, ECSM2 Protein, 1110006O17Rik Protein, endothelial cell surface expressed chemotaxis and apoptosis regulator Protein, ECSCR Protein, Ecscr Protein
- Background
- Endothelial cell-specific chemotaxis receptor (ECSCR) is a cell surface protein expressed by blood endothelial cells with roles in endothelial cell migration and signal transduction. Zebrafish ecscr is expressed in angioblasts and in axial vessels during angioblast migration and vasculogenesis. Morpholino-directed ecscr knockdown resulted in defective angioblast migration in the posterior lateral plate mesoderm, a process known to depend on vascular endothelial-derived growth factor (VEGF).
- Molecular Weight
- 36.8 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- UniProt
- Q19T08
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