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EPH Receptor B3 Protein (EPHB3) (AA 30-554) (His tag)

EPHB3 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274566
  • Target See all EPH Receptor B3 (EPHB3) Proteins
    EPH Receptor B3 (EPHB3)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 30-554
    Origin
    • 13
    • 6
    • 2
    Mouse
    Source
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This EPH Receptor B3 protein is labelled with His tag.
    Purpose
    Mouse EphB3 Protein
    Sequence
    Leu30-Leu554
    Characteristics
    Recombinant Mouse EphB3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu30-Leu554.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    EPH Receptor B3 (EPHB3)
    Alternative Name
    EphB3 (EPHB3 Products)
    Synonyms
    tck Protein, MGC83457 Protein, EPHB3 Protein, ETK2 Protein, HEK2 Protein, TYRO6 Protein, AW456895 Protein, Cek10 Protein, Etk2 Protein, MDK5 Protein, Sek4 Protein, Tyro6 Protein, CEK10 Protein, EK10 Protein, ek3 Protein, ephb3 Protein, fc62d03 Protein, rtk3 Protein, wu:fc62d03 Protein, zek3 Protein, EPH receptor B3 Protein, EPH receptor B3 L homeolog Protein, Eph receptor B3 Protein, eph receptor B3a Protein, Eph receptor tyrosine kinase Protein, EPHB3 Protein, ephb3.L Protein, ephb3 Protein, Ephb3 Protein, ephb3a Protein
    Background
    Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC compared to normal mucosa. Hypermethylation of CpG island is contributed to downregulation of EphB3 in CRC. EphB3 expression in tumor cells may be a useful prognostic indicator for patients with CRC.
    Molecular Weight
    58.4 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.
    UniProt
    P54754
    Pathways
    RTK Signaling
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