FGF21 Protein (AA 29-209) (mFc-Avi Tag,Biotin)
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- Target See all FGF21 Proteins
- FGF21 (Fibroblast Growth Factor 21 (FGF21))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 29-209
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FGF21 protein is labelled with mFc-Avi Tag,Biotin.
- Purpose
- Biotinylated Human FGF21 Protein
- Sequence
- His29-Ser209
- Characteristics
- Recombinant Biotinylated Human FGF21 Protein is expressed from HEK293 with mFc (IgG1) tag and Avi tag at the N-Terminus.It contains His29-Ser209.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Biotinylated Human FGF21, mFc Tag at 2μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Human Beta Klotho, His Tag with the EC50 of 0.26μg/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product FGF21 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FGF21 (Fibroblast Growth Factor 21 (FGF21))
- Alternative Name
- FGF21 (FGF21 Products)
- Synonyms
- FGF21 Protein, fibroblast growth factor 21 Protein, FGF21 Protein, fgf21 Protein, Fgf21 Protein
- Background
- Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several organs and regulates energy homeostasis. Excitement surrounding this relatively recently identified hormone is based on the documented metabolic beneficial effects of FGF21, which include weight loss and improved glycemia.
- Molecular Weight
- 46.9 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9NSA1
- Pathways
- RTK Signaling
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