GIP Protein (AA 22-85) (His tag)
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- Target See all GIP Proteins
- GIP (Gastric Inhibitory Polypeptide (GIP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-85
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GIP protein is labelled with His tag.
- Purpose
- Mouse GIP Protein
- Sequence
- Glu22-Gln85
- Characteristics
- Recombinant Mouse GIP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu22-Gln85.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product GIP Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- GIP (Gastric Inhibitory Polypeptide (GIP))
- Alternative Name
- GIP (GIP Products)
- Synonyms
- GIP Protein, xgip Protein, Gludins Protein, RATGLUDINS Protein, gastric inhibitory polypeptide Protein, gastric inhibitory polypeptide L homeolog Protein, GIP Protein, gip Protein, Gip Protein, gip.L Protein
- Background
- The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic use of GIP was dampened by evidence that its insulinotropic activity was reduced in type 2 diabetes and by reports that it increased glucagon secretion and adipose deposition in non-diabetic individuals.
- Molecular Weight
- 8.7 kDa. Due to glycosylation, the protein migrates to 13-18 kDa based on Tris-Bis PAGE result.
- UniProt
- P48756
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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