GP1BB Protein (AA 27-147) (Fc Tag)

Catalog No. ABIN7274757

Product Details

Target: GP1BB (Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB))

Protein Type: Recombinant

Protein Characteristics: AA 27-147

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This GP1BB protein is labelled with Fc Tag.

Purpose: Mouse GP1BB Protein

Sequence: Pro27-Cys147

Characteristics: Recombinant Mouse GP1BB Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Pro27-Cys147.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: GP1BB (Glycoprotein Ib (Platelet), beta Polypeptide (GP1BB))

Alternative Name: GP1BB (GP1BB Products)

Synonyms: BDPLT1 Protein, BS Protein, CD42C Protein, GPIBB Protein, glycoprotein Ib (platelet), beta polypeptide Protein, glycoprotein Ib platelet beta subunit Protein, glycoprotein Ib, beta polypeptide Protein, GP1BB Protein, Gp1bb Protein

Background: The glycoprotein (GP) Ib-IX complex is the receptor on platelet surfaces that mediates their adhesion to subendothelium. It comprises three polypeptides (GP Ib alpha, GP Ib beta, GP IX), each of which belongs to a superfamily of proteins containing conserved leucine-rich motifs. Association between GP Ib alpha and GP Ib beta was demonstrated biochemically on immunoblots of detergent lysates of CHO alpha beta cells, electrophoresis under nonreducing conditions revealed the two subunits to be covalently linked through a disulfide bond.

Molecular Weight: 39.5 kDa. Due to glycosylation, the protein migrates to 46-50 kDa based on Tris-Bis PAGE result.

UniProt: P56400