GPC2 Protein (AA 22-556) (His tag)
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- Target See all GPC2 Proteins
- GPC2 (Glypican 2 (GPC2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-556
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GPC2 protein is labelled with His tag.
- Purpose
- Mouse Glypican 2/GPC2 Protein
- Sequence
- His22-Ser556
- Characteristics
- Recombinant Mouse Glypican 2/GPC2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His22-Ser556.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Glypican 2 (GPC2) (AA 24-554) protein (His tag)
Crystallography grade GPC2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glypican 2 (GPC2) (AA 22-556) protein (His tag)Crystallography grade GPC2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glypican 2 (GPC2) (AA 22-556) (Active) protein (His tag)GPC2 Origin: Mouse Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Glypican 2 (GPC2) (AA 24-552) (Active) protein (His tag)GPC2 Origin: Rhesus Monkey Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Glypican 2 (GPC2) (AA 24-554) (Active) protein (His tag)GPC2 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Glypican 2 (GPC2) (AA 24-553) protein (Fc Tag)GPC2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- GPC2 (Glypican 2 (GPC2))
- Alternative Name
- Glypican 2 (GPC2 Products)
- Synonyms
- 2410016G05Rik Protein, glypican 2 Protein, glypican 2 (cerebroglycan) Protein, GPC2 Protein, Gpc2 Protein
- Background
- Glypicans can function as coreceptors for multiple signaling molecules known for regulating cell growth, motility, and differentiation. Some members of the glypican family, including glypican 2 (GPC2) and glypican 3 (GPC3), are expressed in childhood cancers and liver cancers, respectively. Antibody-based therapies targeting glypicans are being investigated in preclinical and clinical studies, with the goal of treating solid tumors that do not respond to standard therapies.
- Molecular Weight
- 59.9 kDa. Due to autocatalytic cleavage, the protein migrates to 32-35 kDa based on Tris-Bis PAGE result.
- UniProt
- Q8BKV1
- Pathways
- Glycosaminoglycan Metabolic Process
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