IL17RC Protein (AA 21-467) (Fc Tag)
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- Target See all IL17RC Proteins
- IL17RC (Interleukin 17 Receptor C (IL17RC))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-467
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL17RC protein is labelled with Fc Tag.
- Purpose
- Human IL-17Rc Protein
- Sequence
- Leu21-Arg467
- Characteristics
- Recombinant Human IL-17Rc Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu21-Arg467.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-17A, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 43.5ng/ml determined by ELISA. See testing image for detail.
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Interleukin 17 Receptor C (IL17RC) (AA 21-465) (Active) protein (Fc Tag)
IL17RC Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 17 Receptor C (IL17RC) (AA 1-538) protein (GST tag)IL17RC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 17 Receptor C (IL17RC) (AA 560-791) protein (His tag)Crystallography grade IL17RC Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 17 Receptor C (IL17RC) (AA 486-698) protein (His tag)Crystallography grade IL17RC Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 17 Receptor C (IL17RC) (AA 21-538) protein (His tag)Crystallography grade IL17RC Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 17 Receptor C (IL17RC) (AA 22-464) protein (His tag)Crystallography grade IL17RC Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 17 Receptor C (IL17RC) (AA 21-791) protein (rho-1D4 tag)Crystallography grade IL17RC Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 17 Receptor C (IL17RC) (AA 22-698) protein (rho-1D4 tag)Crystallography grade IL17RC Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IL17RC (Interleukin 17 Receptor C (IL17RC))
- Alternative Name
- IL-17Rc (IL17RC Products)
- Synonyms
- IL17-RL Protein, IL17RL Protein, 1110025H02Rik Protein, Gm19850 Protein, IL-17RC Protein, IL17-RC Protein, Il17rl Protein, interleukin 17 receptor C Protein, Il17rc Protein, IL17RC Protein
- Background
- IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA. IL-17RC protein isoforms are differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer.
- Molecular Weight
- 76.2 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_703190
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