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IL-4 Protein (His-Avi Tag)

IL4 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
Catalog No. ABIN7274950
  • Target See all IL-4 (IL4) Proteins
    IL-4 (IL4) (Interleukin 4 (IL4))
    Protein Type
    Recombinant
    Origin
    • 34
    • 15
    • 10
    • 4
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
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    • 1
    Human
    Source
    • 44
    • 21
    • 16
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL-4 protein is labelled with His-Avi Tag.
    Sequence
    His25-Ser153
    Purity
    > 95% as determined by Tris-Bis PAGE
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human IL-4 at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Human IL-4 R alpha, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product IL4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    Storage
    4 °C,-80 °C
    Storage Comment
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IL-4 (IL4) (Interleukin 4 (IL4))
    Alternative Name
    IL-4 (IL4 Products)
    Synonyms
    IL4 Protein, IL-4 Protein, BCGF-1 Protein, BCGF1 Protein, BSF-1 Protein, BSF1 Protein, Il-4 Protein, Il4e12 Protein, IL2 Protein, interleukin 4 Protein, IL4 Protein, Il4 Protein
    Background
    IL4, IL-4, interleukin 4, MGC79402, pitrakinra, B cell growth factor 1, BCDF, BCGF1, BCGF-1, binetrakin, BSF1, BSF-1, BSF-1,Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. .
    Molecular Weight
    17.8 kDa. Due to glycosylation, the protein migrates to 23-25 kDa based on Tris-Bis PAGE result.
    UniProt
    P05112
    Pathways
    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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