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IL22 Receptor alpha 1 Protein (AA 16-228) (Fc Tag)

IL22RA1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275045
  • Target See all IL22 Receptor alpha 1 (IL22RA1) Proteins
    IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 16-228
    Origin
    • 8
    • 3
    • 3
    • 1
    • 1
    Mouse
    Source
    • 6
    • 5
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL22 Receptor alpha 1 protein is labelled with Fc Tag.
    Purpose
    Mouse IL-22R alpha 1 Protein
    Sequence
    His16-Ala228
    Characteristics
    Recombinant Mouse IL-22R alpha 1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains His16-Ala228.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Mouse IL-22R alpha 1, hFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Mouse IL-22, His Tag with the EC50 of 0.23μg/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product IL22RA1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))
    Alternative Name
    IL-22R alpha 1 (IL22RA1 Products)
    Synonyms
    IL22RA1 Protein, CRF2-9 Protein, IL22R Protein, IL22R1 Protein, 9130219A07Rik Protein, ENSMUSG00000073746 Protein, IL-22R Protein, Il22r Protein, RGD1559655 Protein, interleukin 22 receptor subunit alpha 1 Protein, interleukin 22 receptor, alpha 1 Protein, IL22RA1 Protein, Il22ra1 Protein
    Background
    Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3.
    Molecular Weight
    51.1 kDa. Due to glycosylation, the protein migrates to 65-68 kDa based on Tris-Bis PAGE result.
    UniProt
    Q80XZ4
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