Klotho beta Protein (KLB) (AA 53-994) (His tag)
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- Target See all Klotho beta (KLB) Proteins
- Klotho beta (KLB)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 53-994
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Klotho beta protein is labelled with His tag.
- Purpose
- Mouse Beta Klotho Protein
- Sequence
- Phe53-Pro994
- Characteristics
- Recombinant Mouse Beta Klotho Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe53-Pro994.
- Purity
- > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product KLB Protein
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Klotho beta (KLB) protein (His tag)
KLB Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Klotho beta (KLB) (AA 1-1044) protein (Strep Tag)Crystallography grade KLB Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Klotho beta (KLB) (AA 1-1043) protein (Strep Tag)Crystallography grade KLB Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Klotho beta (KLB) (AA 1-996) protein (His tag)Crystallography grade KLB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Klotho beta (KLB) (AA 1-994) protein (His tag)Crystallography grade KLB Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Klotho beta (KLB)
- Alternative Name
- Beta Klotho (KLB Products)
- Synonyms
- KLB Protein, BKL Protein, AV071179 Protein, betaKlotho Protein, Klb-ps1 Protein, RGD1308227 Protein, klotho beta Protein, KLB Protein, Klb Protein
- Background
- Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites.
- Molecular Weight
- 109.91 kDa. Due to glycosylation, the protein migrates to 120-130 kDa based on Tris-Bis PAGE result.
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding
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