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Lrig1 Protein (AA 35-794) (His tag)

Lrig1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Catalog No. ABIN7275206
  • Target See all Lrig1 Proteins
    Lrig1 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 35-794
    Origin
    • 6
    • 3
    • 1
    Mouse
    Source
    • 6
    • 3
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Lrig1 protein is labelled with His tag.
    Purpose
    Mouse LRIG1 Protein
    Sequence
    Ala35-Thr794
    Characteristics
    Recombinant Mouse LRIG1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala35-Thr794.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
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    Discover our top product Lrig1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Lrig1 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))
    Alternative Name
    LRIG1 (Lrig1 Products)
    Synonyms
    LIG-1 Protein, LIG1 Protein, D6Bwg0781e Protein, Img Protein, leucine rich repeats and immunoglobulin like domains 1 Protein, leucine-rich repeats and immunoglobulin-like domains 1 Protein, LRIG1 Protein, Lrig1 Protein
    Background
    The leucine-rich repeats and immunoglobulin-like domains (LRIG)-1 is a tumor suppressor gene that belongs to the LRIG family. LRIG1 expression has prognostic significance in various human cancers. Somatic mutations, which are associated with a certain rate of response to targeted therapies, are ubiquitously found in human non-small cell lung cancer (NSCLC). LRIG1 was an independent prognostic factor for OS of NSCLC patients. LRIG1 in combination with other clinicopathological risk factors was a stronger prognostic model than clinicopathological risk factors alone.
    Molecular Weight
    84.7 kDa. Due to glycosylation, the protein migrates to 85-110 kDa based on Tris-Bis PAGE result.
    UniProt
    P70193
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