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MFAP5 Protein (AA 22-173) (Fc Tag)

MFAP5 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275231
  • Target See all MFAP5 Proteins
    MFAP5 (Microfibrillar Associated Protein 5 (MFAP5))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 22-173
    Origin
    • 6
    • 4
    • 2
    • 1
    Human
    Source
    • 6
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MFAP5 protein is labelled with Fc Tag.
    Purpose
    Human MFAP5 Protein
    Sequence
    Ile22-Leu173
    Characteristics
    Recombinant Human MFAP5 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile22-Leu173.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product MFAP5 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
    Storage
    -80 °C
    Storage Comment
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MFAP5 (Microfibrillar Associated Protein 5 (MFAP5))
    Alternative Name
    MFAP5 (MFAP5 Products)
    Synonyms
    MFAP5 Protein, MAGP2 Protein, MP25 Protein, MAGP-2 Protein, microfibrillar associated protein 5 Protein, microfibril associated protein 5 Protein, MFAP5 Protein, Mfap5 Protein
    Background
    Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic microfibers and the regulation of endothelial cell behaviors.MFAP5 was significantly overexpressed in BLBC tissues and associated with poor metastasis-free survival of patients with BLBC.
    Molecular Weight
    44.1 kDa. Due to furin cleavage and glycosylation, the protein migrates to 32-38 kDa and 55-65 kDa based on Tris-Bis PAGE result.
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