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MFAP5 Protein (AA 29-164) (Fc Tag)

MFAP5 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275233
  • Target See all MFAP5 Proteins
    MFAP5 (Microfibrillar Associated Protein 5 (MFAP5))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 29-164
    Origin
    • 7
    • 3
    • 2
    • 1
    Mouse
    Source
    • 6
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MFAP5 protein is labelled with Fc Tag.
    Purpose
    Mouse MFAP5 Protein
    Sequence
    Gln29-Leu164
    Characteristics
    Recombinant Mouse MFAP5 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln29-Leu164.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MFAP5 (Microfibrillar Associated Protein 5 (MFAP5))
    Alternative Name
    MFAP5 (MFAP5 Products)
    Synonyms
    MFAP5 Protein, MAGP2 Protein, MP25 Protein, MAGP-2 Protein, microfibrillar associated protein 5 Protein, microfibril associated protein 5 Protein, MFAP5 Protein, Mfap5 Protein
    Background
    Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic microfibers and the regulation of endothelial cell behaviors.MFAP5 was significantly overexpressed in BLBC tissues and associated with poor metastasis-free survival of patients with BLBC.
    Molecular Weight
    42.4 kDa. Due to furin cleavage and glycosylation, the protein migrates to 32-38 kDa and 50-65 kDa based on Tris-Bis PAGE result.
    UniProt
    Q9QZJ6
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