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MARCO Protein (AA 70-518) (His tag)

MARCO Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275279
  • Target See all MARCO Proteins
    MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 70-518
    Origin
    • 4
    • 3
    • 1
    • 1
    • 1
    Mouse
    Source
    • 3
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MARCO protein is labelled with His tag.
    Purpose
    Mouse MARCO Protein
    Sequence
    Gln70-Ser518
    Characteristics
    Recombinant Mouse MARCO Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Gln70-Ser518.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
    Alternative Name
    MARCO (MARCO Products)
    Synonyms
    AI323439 Protein, Ly112 Protein, Scara2 Protein, SCARA2 Protein, macrophage receptor with collagenous structure Protein, MARCO Protein, Marco Protein
    Background
    Scavenger receptor A5 (SCARA5) is a member of the class A scavenger receptors, with most similarity to SCARA1 (SR-A) and SCARA2 (MARCO), which are primarily expressed by macrophages and dendritic cells, in which they participate in clearance of various polyanionic macromolecules, pollution particles, and pathogens.In contrast to expression of SCARA1 and SCARA2 in immune cells, SCARA5 is found in a subset of fibroblast-like cells in the interstitial stroma of most organs, with additional expression in the epithelial cells of testis and choroid plexus
    Molecular Weight
    46.2 kDa. Due to glycosylation, the protein migrates to 48-53 kDa based on Tris-Bis PAGE result.
    Pathways
    Activation of Innate immune Response
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