PAD4 Protein (AA 1-663) (His tag,Biotin)
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- Target See all PAD4 (PADI4) Proteins
- PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-663
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PAD4 protein is labelled with His tag,Biotin.
- Purpose
- Biotinylated Human PADI4 Protein (Primary Amine Labeling)
- Sequence
- Met1-Pro663
- Characteristics
- Recombinant Biotinylated Human PADI4 Protein(Primary Amine Labeling) is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Pro663.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product PADI4 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in LTSB.
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))
- Alternative Name
- PADI4 (PADI4 Products)
- Synonyms
- PAD Protein, PAD4 Protein, PADI5 Protein, PDI4 Protein, PDI5 Protein, Pad4 Protein, Pdi4 Protein, peptidyl arginine deiminase 4 Protein, peptidyl arginine deiminase, type IV Protein, PADI4 Protein, Padi4 Protein
- Background
- Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes.
- Molecular Weight
- 76.6 kDa same as Tris-Bis PAGE result.
- UniProt
- Q9UM07
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