PGLYRP1 Protein (AA 22-196) (Fc Tag)
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- Target See all PGLYRP1 Proteins
- PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-196
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PGLYRP1 protein is labelled with Fc Tag.
- Purpose
- Human PGLYRP1 Protein
- Sequence
- Gln22-Pro196
- Characteristics
- Recombinant Human PGLYRP1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln22-Pro196.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product PGLYRP1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))
- Alternative Name
- PGLYRP1 (PGLYRP1 Products)
- Synonyms
- PGLYRP1 Protein, PGLYRP Protein, pgrp Protein, tag7 Protein, pgrps Protein, pglyrp Protein, pgrp-s Protein, tnfsf3l Protein, MGC108330 Protein, MGC108469 Protein, PGRP-SC1a Protein, si:dkey-113g17.4 Protein, si:ch211-202c21.3 Protein, PGRP Protein, PGRP-S Protein, PGRPS Protein, TAG7 Protein, TNFSF3L Protein, Pglyrp Protein, Tag7 Protein, Tasg7 Protein, Tnfsf3l Protein, Pgrp Protein, peptidoglycan recognition protein 1 Protein, peptidoglycan recognition protein 1 L homeolog Protein, peptidoglycan recognition protein 5 Protein, PGLYRP1 Protein, pglyrp1.L Protein, pglyrp1 Protein, pglyrp5 Protein, Pglyrp1 Protein
- Background
- Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway.
- Molecular Weight
- 46.2 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.
- UniProt
- O75594
- Pathways
- Activation of Innate immune Response
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