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PLA2G7 Protein (AA 22-441) (His tag)

Lp-PLA2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Catalog No. ABIN7275457
  • Target See all PLA2G7 (Lp-PLA2) Proteins
    PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 22-441
    Origin
    • 10
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 10
    • 5
    • 4
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PLA2G7 protein is labelled with His tag.
    Purpose
    Human PLA2G7 Protein
    Sequence
    Phe22-Asn441
    Characteristics
    Recombinant Human PLA2G7 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe22-Asn441.
    Purity
    > 95 % as determined by Tris-Bis PAGE
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product Lp-PLA2 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in 50 mM NaAc, 150 mM NaCl, 10 % Glycerol ( pH 5.0).
    Storage
    -80 °C
    Storage Comment
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
    Alternative Name
    PLA2G7 (Lp-PLA2 Products)
    Synonyms
    LDL-PLA2 Protein, LP-PLA2 Protein, PAFAD Protein, PAFAH Protein, Lp-PLA2 Protein, PAF-AH Protein, R75400 Protein, zgc:77563 Protein, phospholipase A2 group VII Protein, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) Protein, PLA2G7 Protein, Pla2g7 Protein, pla2g7 Protein
    Background
    Endogenous PLA2G7 transcription levels were found to be significantly lower in vascular related cell lines than in the other cell lines. Luciferase reporter gene assays indicated that gene activity was significantly enhanced by PLA2G7 promoter fragment. LA2G7 transcription was found to be up-regulated with the treatment of DAC. The 17-β-estradiol was found to down-regulate PLA2G7 transcription in all the cell lines.
    Molecular Weight
    48.9 kDa. Due to glycosylation, the protein migrates to 49-60 kDa based on Tris-Bis PAGE result.
    UniProt
    Q13093
    Pathways
    Peptide Hormone Metabolism
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