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PLA2G7 Protein (AA 22-440) (His tag)

Lp-PLA2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275462
  • Target See all PLA2G7 (Lp-PLA2) Proteins
    PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 22-440
    Origin
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Mouse
    Source
    • 10
    • 5
    • 4
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PLA2G7 protein is labelled with His tag.
    Purpose
    Mouse PLA2G7 Protein
    Sequence
    Phe22-Asn440
    Characteristics
    Recombinant Mouse PLA2G7 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe22-Asn440.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
    Alternative Name
    PLA2G7 (Lp-PLA2 Products)
    Synonyms
    LDL-PLA2 Protein, LP-PLA2 Protein, PAFAD Protein, PAFAH Protein, Lp-PLA2 Protein, PAF-AH Protein, R75400 Protein, zgc:77563 Protein, phospholipase A2 group VII Protein, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) Protein, PLA2G7 Protein, Pla2g7 Protein, pla2g7 Protein
    Background
    Endogenous PLA2G7 transcription levels were found to be significantly lower in vascular related cell lines than in the other cell lines. Luciferase reporter gene assays indicated that gene activity was significantly enhanced by PLA2G7 promoter fragment. LA2G7 transcription was found to be up-regulated with the treatment of DAC. The 17-β-estradiol was found to down-regulate PLA2G7 transcription in all the cell lines.
    Molecular Weight
    47.9 kDa. Due to glycosylation, the protein migrates to 52-65 kDa based on Tris-Bis PAGE result.
    UniProt
    Q60963
    Pathways
    Peptide Hormone Metabolism
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