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ROR2 Protein (His-Avi Tag,Biotin)

ROR2 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Catalog No. ABIN7275535
  • Target See all ROR2 Proteins
    ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))
    Protein Type
    Recombinant
    Origin
    • 16
    • 6
    • 1
    • 1
    Human
    Source
    • 11
    • 7
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ROR2 protein is labelled with His-Avi Tag,Biotin.
    Sequence
    Val34-Gly403
    Purity
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Anti-ROR2 Antibody, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human ROR2, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA. See testing image for detail.
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    Discover our top product ROR2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    Storage
    4 °C,-80 °C
    Storage Comment
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))
    Alternative Name
    ROR2 (ROR2 Products)
    Synonyms
    BDB Protein, BDB1 Protein, NTRKR2 Protein, Ntrkr2 Protein, mRor2 Protein, ROR2 Protein, bdb Protein, bdb1 Protein, Xror2 Protein, ntrkr2 Protein, MGC97773 Protein, LOC100219935 Protein, ror2 Protein, xror2 Protein, receptor tyrosine kinase like orphan receptor 2 Protein, receptor tyrosine kinase-like orphan receptor 2 Protein, receptor tyrosine kinase like orphan receptor 2 L homeolog Protein, ROR2 Protein, Ror2 Protein, ror2 Protein, ror2.L Protein
    Background
    BDB, BDB1, NTRKR2, ROR2,ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain.
    Molecular Weight
    44.2 kDa. Due to glycosylation, the protein migrates to 54-65 kDa based on Tris-Bis PAGE result.
    UniProt
    A1L4F5
    Pathways
    RTK Signaling, WNT Signaling
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