SARS-CoV NSP3 Protein (AA 1-314) (His-Avi Tag)
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- Target See all SARS-CoV NSP3 products
- SARS-CoV NSP3 (SARS-Coronavirus Nonstructural Protein 3 (SARS-CoV NSP3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-314
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Origin
- SARS Coronavirus (SARS-CoV)
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SARS-CoV NSP3 protein is labelled with His-Avi Tag.
- Purpose
- SARS PLpro/papain-like protease Protein
- Sequence
- Glu1-Ile314
- Characteristics
- Recombinant SARS-CoV-2 PLpro/papain-like protease Protein is expressed from E.coil with His tag and Avi tag at the N-Terminus.It contains Glu1-Ile314.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 20 mM Tris, 100 mM NaCl, 10 % Glycerol ( pH 7.8).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SARS-CoV NSP3 (SARS-Coronavirus Nonstructural Protein 3 (SARS-CoV NSP3))
- Alternative Name
- PLpro (SARS-CoV NSP3 Products)
- Target Type
- Viral Protein
- Background
- The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.
- Molecular Weight
- 38.6 kDa same as Tris-Bis PAGE result.
- UniProt
- P0C6U8
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