SECTM1 Protein (AA 29-145) (Fc Tag)
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- Target See all SECTM1 Proteins
- SECTM1 (Secreted and Transmembrane 1 (SECTM1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 29-145
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SECTM1 protein is labelled with Fc Tag.
- Purpose
- Human SECTM1 Protein
- Sequence
- Gln29-Gly145
- Characteristics
- Recombinant Human SECTM1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln29-Gly145.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SECTM1 (Secreted and Transmembrane 1 (SECTM1))
- Alternative Name
- SECTM1 (SECTM1 Products)
- Synonyms
- K12 Protein, secreted and transmembrane 1 Protein, SECTM1 Protein
- Background
- SECTM1 is a T/NK cell "co-stimulatory" molecule that is expressed in the peripheral blood by neutrophils and monocytes.Human monocytic cells also displayed a pronounced negative regulation of SECTM1 mRNA expression by LPS, while at the protein level SECTM1 expression was also shown to be regulated by IFN and LPS. This tight regulation of SECTM1 gene expression and rapid upregulation highlights its relevance in the innate immune response.
- Molecular Weight
- 39.4 kDa. Due to glycosylation, the protein migrates to 47-50 kDa based on Tris-Bis PAGE result.
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