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SFRP1 Protein (AA 32-314) (His tag)

SFRP1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Catalog No. ABIN7275578
  • Target See all SFRP1 Proteins
    SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 32-314
    Origin
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SFRP1 protein is labelled with His tag.
    Purpose
    Human SFRP1/SARP2 Protein
    Sequence
    Ser32-Lys314
    Characteristics
    Recombinant Human SFRP1/SARP2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser32-Lys314.
    Purity
    > 95 % as determined by Tris-Bis PAGE
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
    Alternative Name
    SFRP1 (SFRP1 Products)
    Synonyms
    FRP Protein, FRP-1 Protein, FRP1 Protein, FrzA Protein, SARP2 Protein, 2210415K03Rik Protein, AW011917 Protein, AW107218 Protein, AW742929 Protein, sFRP-1 Protein, CSFRP1 Protein, SFRP1 Protein, XfrzA Protein, frp Protein, frp-1 Protein, frp1 Protein, frzA Protein, sarp2 Protein, sfrp1 Protein, LOC100231868 Protein, Srfp1a Protein, wu:fd19b09 Protein, secreted frizzled related protein 1 Protein, secreted frizzled-related protein 1 Protein, Secreted frizzled-related protein 1 Protein, secreted frizzled-related protein 1a Protein, secreted frizzled-related protein 1b Protein, SFRP1 Protein, Sfrp1 Protein, sfrp1 Protein, sfrp1a Protein, sfrp1b Protein
    Background
    Secreted frizzled-related protein 1 (SFRP1) is a gene that belongs to the secreted glycoprotein SFRP family. SFRP1 has been classified as a tumor suppressor gene due to the loss of expression in various human cancers, which is mainly attributed by epigenetic inactivation via DNA methylation or transcriptional silencing by microRNAs.
    Molecular Weight
    33.63 kDa. Due to glycosylation, the protein migrates to 43-48 kDa based on Tris-Bis PAGE result.
    UniProt
    Q8N474
    Pathways
    WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation
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