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TFPI2 Protein (AA 23-213) (His tag)

TFPI2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Catalog No. ABIN7275695
  • Target See all TFPI2 Proteins
    TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 23-213
    Origin
    • 9
    • 4
    • 3
    • 2
    Human
    Source
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This TFPI2 protein is labelled with His tag.
    Purpose
    Human TFPI-2 Protein
    Sequence
    Asp23-Lys213.
    Characteristics
    Recombinant Human TFPI-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp23-Lys213.
    Purity
    > 95 % as determined by Tris-Bis PAGE
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product TFPI2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))
    Alternative Name
    TFPI-2 (TFPI2 Products)
    Synonyms
    MGC68843 Protein, TFPI2 Protein, MGC108301 Protein, si:ch211-262k23.2 Protein, tfpi2 Protein, PP5 Protein, REF1 Protein, TFPI-2 Protein, AV000670 Protein, PP5/TFPI-2 Protein, tissue factor pathway inhibitor 2 L homeolog Protein, tissue factor pathway inhibitor 2 Protein, tfpi2.L Protein, TFPI2 Protein, tfpi2 Protein, Tfpi2 Protein
    Background
    Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Moreover, in sputum from cystic fibrosis patients TFPI-2 C-terminal fragments are generated and found associated with immunoglobulins. Together our data describe a previously unknown host defense mechanism and therapeutic importance of TFPI-2 against invading Gram-negative bacterial pathogens.
    Molecular Weight
    22.9 kDa. Due to glycosylation, the protein migrates to 30-35 kDa based on Tris-Bis PAGE result.
    NCBI Accession
    NP_006519
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